ABCG2 rabbit pAb

Cat :A10152

ABCG ,A10152, 10152, ABCG2; ABCP; BCRP; BCRP1; MXR;Breast cancer resistance protein; CDw338

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IF,WB,IHC,ELISA
Reactivity

Human
Dilution

IF: 1:50-200 WB: 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

ABCG2 Polyclonal Antibody detects endogenous levels of ABCG2 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human ABCG2. AA range:461-510
Uniprot No

Q9UNQ0
Alternative names

ABCG2; ABCP; BCRP; BCRP1; MXR; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD338
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

ATP binding cassette subfamily G member 2 (Junior blood group)(ABCG2) Homo sapiens The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
Other

ABCG2, ATP-binding cassette sub-family G member 2; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD338
Mol.Wt (Da)

72314
Concentration

1 mg/ml