Actinin-α1 rabbit pAb

Cat :A10279

Actinin,A10279, 10279, ACTN1, Alpha-actinin-1, ACTN1; Alpha-actinin-1; Alpha-actinin cytoskeletal isoform;

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC
Reactivity

Mouse,Rat
Dilution

WB: 1:1000-2000 IHC: 1:200-500
Storage

-20°C/1 year
Specificity

The antibody detects endogenous Actinin-α1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Recombinant Protein of Actinin-α1
Uniprot No

P12814
Alternative names

ACTN1; Alpha-actinin-1; Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1
Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality

Polyclonal
Isotype

IgG
Background

actinin alpha 1(ACTN1) Homo sapiens Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Other

ACTN1, Alpha-actinin-1
Concentration

1 mg/ml