Actinin-α2/3 rabbit pAb

Cat :A10282

Actinin,A10282, 10282, ACTN2/ACTN3, Alpha-actinin-2/3, ACTN2; Alpha-actinin-2; Alpha-actinin skeletal muscle isoform 2;

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,IF,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Actinin-α2/3 Polyclonal Antibody detects endogenous levels of Actinin-α2/3 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human Actinin alpha-2/3. AA range:31-80
Uniprot No

P35609/Q08043
Alternative names

ACTN2; Alpha-actinin-2; Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein; ACTN3; Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

actinin alpha 2(ACTN2) Homo sapiens Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],
Other

ACTN2/ACTN3, Alpha-actinin-2/3, F-actin cross-linking protein; ACTN3; Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein
Mol.Wt (Da)

103854
Concentration

1 mg/ml