Active Caspase-3 mouse mAb(5E1)

Cat :A10288

Caspase,A10288, 10288, CASP3, Caspase-3, CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Mouse
Applications

IF,WB,IHC
Reactivity

Human,Mouse,Rat,Chicken
Dilution

IF: 1:50-200 WB: 1:500-1000 IHC: 1:100-200
Storage

-20°C/1 year
Specificity

The antibody detects endogenous Active Caspase-3 protein.
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Immunogen

Recombinant Protein of Active Caspase-3
Uniprot No

P42574
Alternative names

CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1
Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality

Monoclonal
Isotype

IgG
Background

caspase 3(CASP3) Homo sapiens This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],
Other

CASP3, Caspase-3; Protein Yama; SREBP cleavage activity 1; SCA-1
Concentration

1 mg/ml