AMACR mouse mAb(4A12)

Cat :A10529

Price： ¥900¥1600

Size： 50ul 100ul

Source

Mouse
Applications

WB,IF,IHC
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:1000 IHC: 1:200 IF 1:200
Storage

-20°C/1 year
Specificity

The antibody detects endogenous AMCAR/P504S proteins.
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen

Synthetic Peptide of AMACR
Uniprot No

Q9UHK6
Alternative names

AMACR; Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase
Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality

Monoclonal
Isotype

IgG
Background

alpha-methylacyl-CoA racemase(AMACR) Homo sapiens This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011],
Other

AMACR, Alpha-methylacyl-CoA racemase
Mol.Wt (Da)

42387
Concentration

1 mg/ml