Amyloid-β rabbit pAb

Cat :A10576

Amyloid,A10576, 10576, APP A4 AD1, Amyloid-β, amyloid beta (A4) precursor protein

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IF,WB,IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300
Storage

-20°C/1 year
Specificity

Amyloid-β Polyclonal Antibody detects endogenous levels of Amyloid-β
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from Amyloid-β at AA range: 221-270
Uniprot No

P05067
Alternative names

amyloid beta (A4) precursor protein
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

amyloid beta precursor protein(APP) Homo sapiens This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014],
Other

APP A4 AD1, Amyloid-β
Mol.Wt (Da)

86943
Concentration

1 mg/ml