APOBEC3A rabbit pAb

Cat :A10714

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    APOBEC3A Polyclonal Antibody detects endogenous levels of APOBEC3A protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human APOBEC3A. AA range:27-76

  • Uniprot No

    P31941

  • Alternative names

    APOBEC3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; Phorbolin-1

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    apolipoprotein B mRNA editing enzyme catalytic subunit 3A(APOBEC3A) Homo sapiens This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided b

  • Other

    APOBEC3A, Probable DNA dC->dU-editing enzyme APOBEC-3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; Phorbolin-1

  • Mol.Wt (Da)

    23012

  • Concentration

    1 mg/ml

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