ASC-1 rabbit pAb

Cat :A10894

ASC,A10894, 10894, TRIP4, Activating signal cointegrator 1, TRIP4; Activating signal cointegrator 1; ASC-1

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,IF,ELISA
Reactivity

Human,Mouse
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

ASC-1 Polyclonal Antibody detects endogenous levels of ASC-1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human TRIP4. AA range:81-130
Uniprot No

Q15650
Alternative names

TRIP4; Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

thyroid hormone receptor interactor 4(TRIP4) Homo sapiens This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1). [provided by RefSeq, Apr 2016],
Other

TRIP4, Activating signal cointegrator 1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4
Mol.Wt (Da)

66146
Concentration

1 mg/ml