AT7L3 rabbit pAb

Cat :A10931

AT7L3 ,A10931, 10931, ATXN7L3, Ataxin-7-like protein 3 (SAGA-associated factor 11 homolog),

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse
Dilution

WB 1:500-2000 ELISA 1:5000-20000
Storage

-20°C/1 year
Specificity

AT7L3 Polyclonal Antibody detects endogenous levels of protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from human protein . at AA range: 40-120
Uniprot No

Q14CW9
Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

domain:The SGF11-type zinc finger mediates the interaction with USP22 and ENY2.,function:Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.,similarity:Belongs to the SGF11 family.,similarity:Contains 1 SCA7 domain.,similarity:Contains 1 SGF11-type zinc finger.,subunit:Component of some SAGA transcription coactivator-HAT complex, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ATXN7L3, ENY2 and USP22 form a subcomplex required for histone deubiquitinylation. Interacts directly with ENY2 and USP22.,
Other

ATXN7L3, Ataxin-7-like protein 3 (SAGA-associated factor 11 homolog)
Concentration

1 mg/ml