ATP-citrate synthase rabbit pAb

Cat :A11024

ATP-citrate synthase ,A11024, 11024, ACLY, ATP-citrate synthase, ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IF,ELISA
Reactivity

Human,Mouse,Rat,Monkey
Dilution

WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

ATP-citrate synthase Polyclonal Antibody detects endogenous levels of ATP-citrate synthase protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human ATP-Citrate Lyase. AA range:420-469
Uniprot No

P53396
Alternative names

ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

ATP citrate lyase(ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],
Other

ACLY, ATP-citrate synthase
Mol.Wt (Da)

120839
Concentration

1 mg/ml