Bestrophin-1 rabbit pAb

Cat :A11212

Bestrophin,A11212, 11212, BEST1, Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2), Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC
Reactivity

Human,Rat,Mouse
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

The antibody detects endogenous Bestrophin-1 protein
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthetic Peptide of Bestrophin-1
Uniprot No

O76090
Alternative names

Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

bestrophin 1(BEST1) Homo sapiens This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008],
Other

BEST1, Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)
Concentration

1 mg/ml