Bub1 rabbit pAb

Cat :A11367

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human,Mouse
Dilution

IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Bub1 Polyclonal Antibody detects endogenous levels of Bub1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human BUB1. AA range:251-300
Uniprot No

O43683
Alternative names

BUB1; BUB1L; Mitotic checkpoint serine/threonine-protein kinase BUB1; hBUB1; BUB1A
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

BUB1 mitotic checkpoint serine/threonine kinase(BUB1) Homo sapiens This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Other

BUB1, Mitotic checkpoint serine/threonine-protein kinase BUB1
Mol.Wt (Da)

122375
Concentration

1 mg/ml