C3G (phospho Tyr504) rabbit pAb

Cat :A11418

C3G,A11418, 11418, RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1; CRK SH3-binding GNRP

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-C3G (Y504) Polyclonal Antibody detects endogenous levels of C3G protein only when phosphorylated at Y504.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human RapGEF1 around the phosphorylation site of Tyr504. AA range:470-519
Uniprot No

Q13905
Alternative names

RAPGEF1; GRF2; Rap guanine nucleotide exchange factor 1; CRK SH3-binding GNRP; Guanine nucleotide-releasing factor 2; Protein C3G
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

Rap guanine nucleotide exchange factor 1(RAPGEF1) Homo sapiens This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008],
Other

RAPGEF1, Rap guanine nucleotide exchange factor 1; Guanine nucleotide-releasing factor 2; Protein C3G
Mol.Wt (Da)

120548
Concentration

1 mg/ml