CA VIII rabbit pAb

Cat :A11439

CA VIII ,A11439, 11439, CA8, CALS; Carbonic anhydrase-related protein; CARP; Carbonic anhydrase VIII; CA-VIII

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

CA VIII Polyclonal Antibody detects endogenous levels of CA VIII protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from the Internal region of human CA VIII.
Uniprot No

P35219
Alternative names

CA8; CALS; Carbonic anhydrase-related protein; CARP; Carbonic anhydrase VIII; CA-VIII
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

carbonic anhydrase 8(CA8) Homo sapiens The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provid
Other

CA8, Carbonic anhydrase-related protein
Mol.Wt (Da)

32973
Concentration

1 mg/ml