Caspase12 rabbit pAb

Cat :A11630

Caspase-12,Caspase12,Caspase 12,A11630, 11630, CASP12, Inactive caspase-12,

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Caspase12 Polyclonal Antibody detects endogenous levels of Caspase12 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase12. AA range:50-99
Uniprot No

Q6UXS9
Alternative names

CASP12; Inactive caspase-12; CASP-12
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

caspase 12 (gene/pseudogene)(CASP12) Homo sapiens Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011],
Other

CASP12, Inactive caspase-12
Mol.Wt (Da)

38907/29429
Concentration

1 mg/ml