Cathepsin L rabbit pAb

Cat :A11689

Cathepsin,A11689, 11689, CTSL1, Cathepsin L1, CTSL1; CTSL; Cathepsin L1; Major excreted protein; MEP

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Cathepsin L Polyclonal Antibody detects endogenous levels of Cathepsin L protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from the Internal region of human Cathepsin L.
Uniprot No

P07711
Alternative names

CTSL1; CTSL; Cathepsin L1; Major excreted protein; MEP
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

cathepsin L(CTSL) Homo sapiens The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012],
Other

CTSL1, Cathepsin L1
Mol.Wt (Da)

37564
Concentration

1 mg/ml