CD45 mouse mAb(12A9)

Cat :A12051

CD45,A12051, 12051, PTPRC, Receptor-type tyrosine-protein phosphatase C, PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD45

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Mouse
Applications

IF,WB,IHC,
Reactivity

Human
Dilution

IF: 1:50-200 WB: 1:2000 IHC 1:50-300
Storage

-20°C/1 year
Specificity

The antibody detects endogenous CD45 proteins.
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen

Synthetic Peptide of CD45
Uniprot No

P08575
Alternative names

PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD45
Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality

Monoclonal
Isotype

IgG
Background

protein tyrosine phosphatase, receptor type C(PTPRC) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which enc
Other

PTPRC, Receptor-type tyrosine-protein phosphatase C
Mol.Wt (Da)

147254
Concentration

1 mg/ml