CDA7L rabbit pAb

Cat :A12117

CDA7L ,A12117, 12117, CDCA7L HR1 JPO2 R1, Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2),

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human
Dilution

WB 1:500-2000 ELISA 1:5000-20000
Storage

-20°C/1 year
Specificity

CDA7L Polyclonal Antibody detects endogenous levels of protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from human protein . at AA range: 140-220
Uniprot No

Q96GN5
Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

function:Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.,induction:By MYC overexpression in a concentration dependent manner in neuroblastoma cell line.,miscellaneous:Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell lines. CDCA7L overexpression induces colony formation.,subcellular location:Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.,subunit:Interacts with MYC and PSIP1.,tissue specificity:Ubiquitous. Overexpressed in medulloblastoma.,
Other

CDCA7L HR1 JPO2 R1, Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2)
Concentration

1 mg/ml