CDO1 rabbit pAb

Cat :A12222

CDO1 ,A12222, 12222, CDO1, Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I),

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB 1:500-2000 ELISA 1:5000-20000
Storage

-20°C/1 year
Specificity

CDO1 Polyclonal Antibody detects endogenous levels of protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from part region of human protein
Uniprot No

Q16878
Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

catalytic activity:L-cysteine + O(2) = 3-sulfinoalanine.,cofactor:Binds 1 iron ion per subunit. Zinc to a much lesser extent.,cofactor:IRON; NAD(P)H.,function:Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range.,induction:In hepatoblastoma HepG2 cells, down-regulated by phorbol 12-myristate 13-acetate.,pathway:Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.,PTM:The thioether cross-link between Cys-93 and Tyr-157 plays a structural role through stabilizing the Fe(2+) ion, and prevents the production of highly damaging free hydroxyl radicals by holding the oxygen radical via hydroxyl hydrogen.,similarity:Belongs to the cysteine dioxygenase family.,subunit:Monomer.,tissue specificity:Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma HepG2 cells.,
Other

CDO1, Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I)
Concentration

1 mg/ml