CFC1B rabbit pAb

Cat :A12325

CFC1B ,A12325, 12325, CFC1B, Cryptic family protein 1B,

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human
Dilution

WB 1:500-2000 ELISA 1:5000-20000
Storage

-20°C/1 year
Specificity

CFC1B Polyclonal Antibody detects endogenous levels of protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from part region of human protein
Uniprot No

P0CG36
Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

disease:Defects in CFC1 are a cause of conotruncal heart malformations (CTHM) [MIM:217095]. CTHM consist of cardiac outflow tract defects, such as tetralogy of Fallot, pulmonary atresia, double-outlet right ventricle, truncus arteriosus communis, and aortic arch anomalies.,disease:Defects in CFC1 are a cause of transposition of the great arteries, dextro-looped (DTGA) [MIM:608808]. The more common form of DTGA, consists of complete inversion of the great vessels, so that the aorta incorrectly arises from the right ventricle and the pulmonary artery incorrectly arises from the left ventricle. This creates completely separate pulmonary and systemic circulatory systems, an arrangement that is incompatible with life. Patients often have atrial and/or ventricular septal defects or other types of shunting that allow some mixing between the circulations in order to support life minimally, but surgical intervention is always required.,disease:Defects in CFC1 are a cause of visceral heterotaxy (HTX2) [MIM:605376]. HTX2 is an autosomal form of visceral heterotaxy (HTX). HTX is characterized by a variable group of congenital anomalies that include complex cardiac malformations and situs inversus or situs ambiguus.,function:Involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation.,PTM:N-glycosylated.,similarity:Contains 1 EGF-like domain.,
Other

CFC1B, Cryptic family protein 1B
Concentration

1 mg/ml