CHOP mouse mAb(2B1)

Cat :A12418

Price： ¥900¥1600

Size： 50ul 100ul

Source

Mouse
Applications

WB,IF,IHC
Reactivity

Human,Rat,Mouse
Dilution

WB 1:1000-2000, IHC 1:100-200 IF 1:200
Storage

-20°C/1 year
Specificity

CHOP protein detects endogenous levels of DDIT3
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen

Synthetic Peptide of CHOP at AA range of 10-90
Uniprot No

P35638
Alternative names

DDIT3
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Monoclonal
Isotype

IgG
Background

DNA damage inducible transcript 3(DDIT3) Homo sapiens This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010],
Other

DDIT3, DDIT3
Concentration

1 mg/ml