Claudin 11 Antibody

Cat :A12534

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB 1:500-2000, ELISA 1:10000-20000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of Claudin 11 Antibody

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from human Claudin 11

  • Uniprot No

    O75508

  • Alternative names

    Claudin-11 (Oligodendrocyte-specific protein)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    claudin 11(CLDN11) Homo sapiens This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different iso

  • Other

    CLDN11 OSP OTM, Claudin-11 (Oligodendrocyte-specific protein)

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images