Claudin-3 (phospho Tyr219) rabbit pAb

Cat :A12543

Claudin,A12543, 12543, CLDN3, C7orf1; CPETR2; Claudin-3; Clostridium perfringens enterotoxin receptor 2

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-Claudin-3 (Y219) Polyclonal Antibody detects endogenous levels of Claudin-3 protein only when phosphorylated at Y219.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human Claudin 3 around the phosphorylation site of Tyr219. AA range:171-220
Uniprot No

O15551
Alternative names

CLDN3; C7orf1; CPETR2; Claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; Rat ventral prostate.1 protein homolog; hRVP1
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

claudin 3(CLDN3) Homo sapiens Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008],
Other

CLDN3, Claudin-3; CPE-R 2; CPE-receptor 2; Rat ventral prostate.1 protein homolog; hRVP1
Mol.Wt (Da)

23319
Concentration

1 mg/ml