Cleaved-CD97β (S531) rabbit pAb

Cat :A12624

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Cleaved-CD97β (S531) Polyclonal Antibody detects endogenous levels of fragment of activated CD97β protein resulting from cleavage adjacent to S531.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human CD97 beta. AA range:512-561

  • Uniprot No

    P48960

  • Alternative names

    CD97; CD97 antigen; Leukocyte antigen CD97; CD antigen CD97

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    adhesion G protein-coupled receptor E5(ADGRE5) Homo sapiens This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 1

  • Other

    CD97, CD97 antigen

  • Mol.Wt (Da)

    91869

  • Concentration

    1 mg/ml

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