COL18A1 rabbit pAb

Cat :A12816

COL18A,A12816, 12816, COL18A1, Collagen alpha-1(XVIII) chain, COL18A1; Collagen alpha-1(XVIII) chain

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IHC,IF,ELISA
Reactivity

Human,Mouse
Dilution

IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

COL18A1 Polyclonal Antibody detects endogenous levels of COL18A1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen XVIII alpha1. AA range:801-850
Uniprot No

P39060
Alternative names

COL18A1; Collagen alpha-1(XVIII) chain
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

collagen type XVIII alpha 1 chain(COL18A1) Homo sapiens This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
Other

COL18A1, Collagen alpha-1(XVIII) chain
Mol.Wt (Da)

178160
Concentration

1 mg/ml