Collagen I mouse mAb(5B7)

Cat :A12852

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Mouse

  • Applications

    IHC

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    IHC 1:50-300

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous Collagen I protein

  • Source/Purification

    The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthetic Peptide of Collagen I

  • Uniprot No

    P02452

  • Alternative names

    Collagen alpha-1(I) chain (Alpha-1 type I collagen)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Monoclonal

  • Isotype

    IgG

  • Background

    collagen type I alpha 1 chain(COL1A1) Homo sapiens This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008],

  • Other

    COL1A1, Collagen alpha-1(I) chain (Alpha-1 type I collagen)

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images