Collagen I rabbit pAb

Cat :A12854

Collagen,A12854, 12854, , Collagen I, collagen, type I, alpha 2

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB 1:500-2000, ELISA 1:10000-20000
Storage

-20°C/1 year
Specificity

Collagen I Polyclonal Antibody detects endogenous levels of Collagen I
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from Collagen I . at AA range: 1200-1217
Uniprot No

P08123/P02452
Alternative names

collagen, type I, alpha 2
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

collagen type I alpha 2 chain(COL1A2) Homo sapiens This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008],
Other

, Collagen I
Concentration

1 mg/ml