Collagen IV rabbit pAb

Cat :A12861

Collagen,A12861, 12861, COL4A1, Collagen IV, collagen, type IV, alpha 1

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB 1:500-2000, ELISA 1:10000-20000
Storage

-20°C/1 year
Specificity

Collagen IV Polyclonal Antibody detects endogenous levels of Collagen IV
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from Collagen IV . at AA range: 1620-1670
Uniprot No

P02462
Alternative names

collagen, type IV, alpha 1
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

collagen type IV alpha 1 chain(COL4A1) Homo sapiens This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
Other

COL4A1, Collagen IV
Concentration

1 mg/ml