Collagen IV mouse mAb(5C9)

Cat :A12863

Collagen,A12863, 12863, COL4A1, Collagen alpha-1(IV) chain [Cleaved into: Arresten], Collagen alpha-1(IV) chain [Cleaved into: Arresten]

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Mouse
Applications

IHC
Reactivity

Human,Mouse,Rat
Dilution

IHC 1:50-300
Storage

-20°C/1 year
Specificity

The antibody detects endogenous Collagen IV protein
Source/Purification

The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthetic Peptide of Collagen IV
Uniprot No

p02462
Alternative names

Collagen alpha-1(IV) chain [Cleaved into: Arresten]
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Monoclonal
Isotype

IgG
Background

collagen type IV alpha 1 chain(COL4A1) Homo sapiens This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
Other

COL4A1, Collagen alpha-1(IV) chain [Cleaved into: Arresten]
Concentration

1 mg/ml