Cyclin A rabbit pAb

Cat :A13226

Cyclin,A13226, 13226, CCNA1/CCNA2, Cyclin-A1/2, CCNA1; Cyclin-A1; CCNA2; CCN1; CCNA; Cyclin-A2; Cyclin-A

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,IF,ELISA
Reactivity

Human,Mouse,Rat,Monkey
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Cyclin A Polyclonal Antibody detects endogenous levels of Cyclin A protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human Cyclin A. AA range:221-270
Uniprot No

P78396/P20248
Alternative names

CCNA1; Cyclin-A1; CCNA2; CCN1; CCNA; Cyclin-A2; Cyclin-A
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

cyclin A1(CCNA1) Homo sapiens The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multi
Other

CCNA1/CCNA2, Cyclin-A1/2
Mol.Wt (Da)

52358/48537
Concentration

1 mg/ml