CYP1A2 rabbit pAb

Cat :A13283

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    IHC,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    CYP1A2 Polyclonal Antibody detects endogenous levels of CYP1A2 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human Cytochrome P450 1A2. AA range:331-380

  • Uniprot No

    P05177

  • Alternative names

    CYP1A2; Cytochrome P450 1A2; CYPIA2; Cytochrome P(3)450; Cytochrome P450 4; Cytochrome P450-P3

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    cytochrome P450 family 1 subfamily A member 2(CYP1A2) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008],

  • Other

    CYP1A2, Cytochrome P450 1A2

  • Mol.Wt (Da)

    58294

  • Concentration

    1 mg/ml

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