DSE rabbit pAb

Cat :A13776

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB
Reactivity

Human, Mouse
Dilution

WB 1:500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of DSE at Human/Mouse
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human DSE
Uniprot No

Q9UL01
Alternative names

Dermatan-sulfate epimerase (DS epimerase) (EC 5.1.3.19) (Chondroitin-glucuronate 5-epimerase) (Squamous cell carcinoma antigen recognized by T-cells 2) (SART-2)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.249% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016],
Other

DSE SART2, DSE
Concentration

1 mg/ml