DUX4 rabbit pAb

Cat :A13803

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB
Reactivity

Human
Dilution

WB 1：500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of DUX4 at Human
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human DUX4
Uniprot No

Q9UBX2
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
Other

DUX4 DUX10, DUX4
Mol.Wt (Da)

46640
Concentration

1 mg/ml