E2F-1 (Acetyl-Lys120) rabbit pAb

Cat :A13847

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human:K120,Mouse:K115,Rat:K118

  • Dilution

    WB: 1:500-10000 ELISA: 1:10000

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous E2F-1 (Acetyl-Lys120) protein

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized acetyl-peptide from human protein at AA range: 100-170

  • Uniprot No

    Q01094

  • Alternative names

    E2F1 RBBP3

  • Form

    PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    E2F transcription factor 1(E2F1) Homo sapiens The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media

  • Other

    E2F1 RBBP3, E2F transcription factor 1

  • Mol.Wt (Da)

    46920

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images