E2F-4/5 rabbit pAb

Cat :A13855

E2F,A13855, 13855, E2F4/E2F5, Transcription factor E2F4/5, E2F4; Transcription factor E2F4; E2F-4; E2F5; Transcription factor E2F5; E2F-5

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human,Mouse,Rat,Monkey
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

E2F-4/5 Polyclonal Antibody detects endogenous levels of E2F-4/5 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human E2F4. AA range:51-100
Uniprot No

Q16254/Q15329
Alternative names

E2F4; Transcription factor E2F4; E2F-4; E2F5; Transcription factor E2F5; E2F-5
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

E2F transcription factor 4(E2F4) Homo sapiens The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated ge
Other

E2F4/E2F5, Transcription factor E2F4/5
Mol.Wt (Da)

43960/37610
Concentration

1 mg/ml