EWS rabbit pAb

Cat :A14278

EWS ,A14278, 14278, EWSR1, RNA-binding protein EWS, EWSR1; EWS; RNA-binding protein EWS; EWS oncogene; Ewing sarcoma breakpoint region 1 protein

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

EWS Polyclonal Antibody detects endogenous levels of EWS protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human EWSR1. AA range:403-452
Uniprot No

Q01844
Alternative names

EWSR1; EWS; RNA-binding protein EWS; EWS oncogene; Ewing sarcoma breakpoint region 1 protein
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

EWS RNA binding protein 1(EWSR1) Homo sapiens This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been id
Other

EWSR1, RNA-binding protein EWS
Mol.Wt (Da)

68478
Concentration

1 mg/ml