FAT1 rabbit pAb

Cat :A14474

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    IHC

  • Reactivity

    Human

  • Dilution

    IHC 1:50-300

  • Storage

    -20°C/1 year

  • Specificity

    FAT1 Polyclonal Antibody detects endogenous levels of protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from human protein . at AA range: 1140-1220

  • Uniprot No

    Q14517

  • Form

    Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    FAT atypical cadherin 1(FAT1) Homo sapiens This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq, Jul 2008],

  • Other

    FAT1 CDHF7 FAT, Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images