FBX32 rabbit pAb

Cat :A14495

FBX32 ,A14495, 14495, FBXO32, FBX32, F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB
Reactivity

Human, Mouse,Rat
Dilution

WB 1:500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of FBX32 at Human/Mouse/Rat
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human FBX32
Uniprot No

Q969P5
Alternative names

F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.66% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],
Other

FBXO32, FBX32
Concentration

1 mg/ml