GABA A Receptor α4 rabbit pAb

Cat :A14846

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    WB,IHC

  • Reactivity

    Human,Rat,Mouse

  • Dilution

    WB 1:1000-2000, IHC 1:100-200

  • Storage

    -20°C/1 year

  • Specificity

    GABA A Receptor α4 protein(A226) detects endogenous levels of GABA A Receptor α4

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthetic Peptide of GABA A Receptor α4

  • Uniprot No

    P48169

  • Alternative names

    GABRA4; Gamma-aminobutyric acid receptor subunit alpha-4; GABA(A) receptor subunit alpha-4

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    gamma-aminobutyric acid type A receptor alpha4 subunit(GABRA4) Homo sapiens Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011],

  • Other

    GABRA4, Gamma-aminobutyric acid receptor subunit alpha-4 (GABA(A) receptor subunit alpha-4)

  • Concentration

    1 mg/ml

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