Rabbit
WB,IF,ELISA
Human,Mouse,Rat
WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
-20°C/1 year
GluR-δ2 Polyclonal Antibody detects endogenous levels of GluR-δ2 protein.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
The antiserum was produced against synthesized peptide derived from human GRID2. AA range:831-880
O43424
GRID2; GLURD2; Glutamate receptor delta-2 subunit; GluR delta-2 subunit
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Polyclonal
IgG
glutamate ionotropic receptor delta type subunit 2(GRID2) Homo sapiens The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this
GRID2, Glutamate receptor delta-2 subunit
113431
1 mg/ml
Product | Reactivity | Applications | Conjugation | Catalog | Images |
---|