Rabbit
WB,ELISA
Human,Mouse,Rat
WB: 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
-20°C/1 year
GPS2 Polyclonal Antibody detects endogenous levels of GPS2 protein.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
The antiserum was produced against synthesized peptide derived from human GPS2. AA range:11-60
Q13227
GPS2; G protein pathway suppressor 2; GPS-2
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Polyclonal
IgG
G protein pathway suppressor 2(GPS2) Homo sapiens This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008],
GPS2, G protein pathway suppressor 2
36689
1 mg/ml
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