HDAC5 (phospho Ser498) rabbit pAb

Cat :A15535

HDAC,A15535, 15535, HDAC5, Histone deacetylase 5, HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,IF,ELISA
Reactivity

Human,Mouse
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-HDAC5 (S498) Polyclonal Antibody detects endogenous levels of HDAC5 protein only when phosphorylated at S498.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser498. AA range:464-513
Uniprot No

Q9UQL6
Alternative names

HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

histone deacetylase 5(HDAC5) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Other

HDAC5, Histone deacetylase 5
Mol.Wt (Da)

121992
Concentration

1 mg/ml