HER2 mouse mAb(11H9)

Cat :A15569

HER2,A15569, 15569, ERBB2, Receptor tyrosine-protein kinase erbB-2, ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cel

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Mouse
Applications

WB,IF,IHC
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:2000-4000 IHC: 1:200 IF 1:200
Storage

-20°C/1 year
Specificity

The antibody detects endogenous ErbB-2/HER-2 proteins.
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen

Synthetic Peptide of HER2
Uniprot No

P04626
Alternative names

ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340
Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality

Monoclonal
Isotype

IgG
Background

erb-b2 receptor tyrosine kinase 2(ERBB2) Homo sapiens This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding d
Other

ERBB2, Receptor tyrosine-protein kinase erbB-2
Mol.Wt (Da)

137910
Concentration

1 mg/ml