HIRA rabbit pAb

Cat :A15614

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human,Mouse
Dilution

IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

HIRA Polyclonal Antibody detects endogenous levels of HIRA protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human HIRA. AA range:521-570
Uniprot No

P54198
Alternative names

HIRA; DGCR1; HIR; TUPLE1; Protein HIRA; TUP1-like enhancer of split protein 1
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

histone cell cycle regulator(HIRA) Homo sapiens This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008],
Other

HIRA, Protein HIRA
Mol.Wt (Da)

111835
Concentration

1 mg/ml