HLA-DOβ rabbit pAb

Cat :A15775

HLA ,A15775, 15775, HLA-DOB, HLA class II histocompatibility antigen DO beta chain, HLA-DOB; HLA class II histocompatibility antigen; DO beta chain; MHC class II antigen DOB

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

HLA-DOβ Polyclonal Antibody detects endogenous levels of HLA-DOβ protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human HLA-DOB. AA range:1-50
Uniprot No

P13765
Alternative names

HLA-DOB; HLA class II histocompatibility antigen; DO beta chain; MHC class II antigen DOB
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

major histocompatibility complex, class II, DO beta(HLA-DOB) Homo sapiens HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008],
Other

HLA-DOB, HLA class II histocompatibility antigen DO beta chain
Mol.Wt (Da)

30822
Concentration

1 mg/ml