IgA rabbit pAb

Cat :A16099

IgA ,A16099, 16099, IGHA1/IGHA2, Ig alpha-1 chain C region/Ig alpha-2 chain C region, IGHA1; Ig alpha-1 chain C region; IGHA2; Ig alpha-2 chain C region

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

IgA Polyclonal Antibody detects endogenous levels of IgA protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human IgA. AA range:227-276
Uniprot No

P01876/P01877
Alternative names

IGHA1; Ig alpha-1 chain C region; IGHA2; Ig alpha-2 chain C region
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

disease:A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.,function:Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.,PTM:3-Hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.,similarity:Contains 3 Ig-like (immunoglobulin-like) domains.,subunit:Monomeric or polymeric.,
Other

IGHA1/IGHA2, Ig alpha-1 chain C region/Ig alpha-2 chain C region
Mol.Wt (Da)

37655
Concentration

1 mg/ml