IGF-IIR rabbit pAb

Cat :A16117

IGF,A16117, 16117, IGF2R, Cation-independent mannose-6-phosphate receptor, IGF2R; MPRI; Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300;Insulin-like growth factor 2 receptor

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

IGF-IIR Polyclonal Antibody detects endogenous levels of IGF-IIR protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human IGF2R. AA range:2251-2300
Uniprot No

P11717
Alternative names

IGF2R; MPRI; Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300;Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; CD222
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

insulin like growth factor 2 receptor(IGF2R) Homo sapiens This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015],
Other

IGF2R, Cation-independent mannose-6-phosphate receptor
Mol.Wt (Da)

274276
Concentration

1 mg/ml