IL-10 rabbit pAb

Cat :A16172

IL-10 ,A16172, 16172, IL10, Interleukin-10, IL10; Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

IL-10 Polyclonal Antibody detects endogenous levels of IL-10 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human IL10. AA range:71-120
Uniprot No

P22301
Alternative names

IL10; Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

interleukin 10(IL10) Homo sapiens The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011],
Other

IL10, Interleukin-10
Mol.Wt (Da)

20517
Concentration

1 mg/ml