JMY rabbit pAb

Cat :A16547

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse
Dilution

WB: 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

JMY Polyclonal Antibody detects endogenous levels of JMY protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human JMY. AA range:931-980
Uniprot No

Q8N9B5
Alternative names

JMY; Junction-mediating and -regulatory protein
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

function:Cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage.,induction:By E2F.,PTM:Ubiquitinated by MDM2, leading to its subsequent degradation by the proteasome. In case of DNA damage, the interaction with MDM2 is altered, preventing degradation and allowing interaction with p300/EP300 and its function in p53/TP53 stress response.,similarity:Contains 1 WH2 domain.,subunit:Interacts with p300/EP300, the complex being recruited to activated p53/TP53. Interacts with TTC5.,
Other

JMY, Junction-mediating and -regulatory protein
Mol.Wt (Da)

71826
Concentration

1 mg/ml