KAISO rabbit pAb

Cat :A16597

KAISO ,A16597, 16597, ZBTB33 KAISO ZNF348, Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33),

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse
Dilution

WB 1:500-2000 ELISA 1:5000-20000
Storage

-20°C/1 year
Specificity

KAISO Polyclonal Antibody detects endogenous levels of protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from human protein . at AA range: 100-180
Uniprot No

Q86T24
Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

zinc finger and BTB domain containing 33(ZBTB33) Homo sapiens This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-&#945;2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear impor
Other

ZBTB33 KAISO ZNF348, Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33)
Concentration

1 mg/ml